![]() ![]() On the contrary, the on-chip process based on antibodies could capture only partially the antibiotics, as well as the protocol based on beads functionalized with small groups specific for sulfonamides. These solutions of purified antibiotics are particularly suitable for further analyses, for example, with innovative methods, such as label-free detection. ![]() The most promising results are obtained employing the functionalization with aptamers, which are able not only to capture and release almost all tetracycline present in the initial sample but also to deliver an enriched and simplified solution of antibiotic. The setup of these different strategies as well as the performance of the different functionalizations are carefully evaluated and compared. The microbeads are functionalized either with aptamers, antibodies or small functional groups able to interact with specific antibiotics. Here, a microfluidic method based on the use of magnetic microbeads specifically functionalized and inserted in polymeric microchambers is proposed. In the context of food safety, new methods based on microfluidics could offer better performance, providing improved rapidity, portability and sustainability, being more cost effective and easy to use. ![]() The presence of residual antibiotics in food is increasingly emerging as a worrying risk for human health both for the possible direct toxicity and for the development of antibiotic-resistant bacteria. ![]()
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